منابع مشابه
Characterization of human papovavirus RFV: comparison with SV40 and BKV.
Human papovavirus, RFV, isolated from urine of a renal transplant patient was compared with two strains of SV40 and with the prototype human papovavirus, BKV. Neutralization tests showed that RFV and BKV are indistinguishable, while large-plaque (LP) and small-plaque(SP) isolates of SV40 gave a low but significant level of cross-reaction with rabbit or human antisera against RFV. DNA reassociat...
متن کاملHuman polyomavirus BKV and renal disease.
Urinary shedding of BKV is increased in immunocomIn 1971, two human polyomaviruses were discovered, BK virus (BKV ) from the urine of a renal transplant promising conditions. BKV infection has been linked to occasional cases of cystitis in immunocompetent recipient (whose initials were B.K.) and JC virus (JCV ) from the brain of a patient (whose initials were J.C.) children, to glomerulonephrit...
متن کاملAnalysis of origin of DNA replication of human papovavirus BK.
We have analyzed the cis-acting sequence elements and properties of the origin of DNA replication of human papovavirus BK (BKV). The precise boundaries of the origin varied, depending on the cell type and the viral T antigen used for assay. The BKV minimal origin of replication consisted of an inverted repeat, T-antigen-binding site II, and a 20-base-pair AT block when assayed in monkey kidney ...
متن کاملidentification and discovery of novel micrornas in the human genome
although more than 98% of the human genome is transcribed, most of these transcripts are not translated into proteins. rather, they are considered as non-coding rnas. micrornas (mirnas) are very short non-coding rnas approximately 22 nucleotides in length which regulate many key processes of cells such as growth, proliferation, differentiation, cell cycle, apoptosis (programmed cell death) and ...
متن کاملIncomplete Simian Papovavirus Sv40
A study was made of the effects of 5-fluorouracil (FU) and 5-fluorodeoxyuridine (FUDR) on the replication of the simian papovavirus SV40 in cercopithecus monkey kidney cells and on the production of virus antigen by these cells. Both drugs markedly suppressed the production of new infectious virus by SV40-infected cells. Synthesis of viral protein was also markedly suppressed by FUDR, but not b...
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ژورنال
عنوان ژورنال: Cell
سال: 1979
ISSN: 0092-8674
DOI: 10.1016/0092-8674(79)90209-5